The DMS48 is a test of visual
recognition
memory test designed for the assessment of early Alzheimers
disease. The
hypotheses underlying the development of the DMS48 can be found in the
first paragraphs
of the original article in Neurology (Barbeau et al, 2004). Similar ideas were fully developped in a recent opinion paper (Didic et al, 2011).Downloading the DMS48
The DMS48 can be downloaded
and used freely.
Downloading (you will need
Set 1, Set 2 and
the recording sheets, Set 3 is optional)
-
Set 1
-
Set 2
-
Set 3
Instructions
and normalization of this test
were published in Barbeau E, Tramoni E, Joubert S, Mancini J, Ceccaldi
M,
Poncet M. (2004). Évaluation
de la
mémoire de reconnaissance visuelle : normalisation
dune nouvelle épreuve
en choix forcé et utilité en neuropsychologie
clinique. In Van-der-Linden M et
Gremem (Eds). L'évaluation des troubles de la
mémoire. Présentation de quatre
tests de mémoire épisodique (avec leur
étalonnage). Marseille,
éditions Solal. p
85-101. The norms were
acquired in French subjects.
Recent norms in French people can be found in this article: Rullier L, Matharan
F, Barbeau EJ, Mokri H, Dartigues JF, Pérès K, Amieva H. (2014). Test
du DMS 48 : normes chez les sujets âgés et propriétés de détection de
la maladie dAlzheimer dans la cohorte AMI. Gériatrie et Psychologie
Neuropsychiatrie du Vieillissement, 12(3), 321-330. A shorten English version of the instructions and
norms can be
found here . Coming soon: parallel versions of the DMS48! Ask if you need them.Research articles on the DMS48 by our group
| Note
that studies using the DMS48 have been published by other groups,
including in other conditions than Alzheimer. Type "DMS48" in
GoogleScholar to find out more. |
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De
Anna F, Didic M, Barbeau EJ, Mancini J, Felician O, Ceccaldi M. (2014).
Increasing cognitive changes during follow-up in amnestic Mild
Cognitive Impairment patients with impaired visual recognition memory.
Neuropsychology, 28(1): 98-105. |
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Didic M, Felician O, Barbeau EJ, Mancini J, Latger-Florence C, Poncet M, Ceccaldi M. (2013). Impaired visual recognition memory predicts Alzheimers disease in amnestic MCI. Dementia and Geriatric Cognitive Disorders, 35, 291-299. |
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Didic M, Barbeau EJ, Felician O, Tramoni E, Guedj E, Poncet M, Ceccaldi M. (2011). Which memory system is impaired first in AD? Journal of Alzheimer's disease, 27(1), 11-22. |
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Didic-Hamel Cooke M, Ranjeva JP, Barbeau EJ, Confort-Gouny S, Le Fur Y, Felician O, Poncet M, Ceccaldi M, Cozzone PJ. (2010). Impaired visual recognition memory in amnestic MCI is associated with subhippocampal metabolic changes on MRSI. Journal of Alzheimer's disease, 22(4), 1268-1279. |
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Barbeau EJ, Ranjeva PJ, Didic M, Confort-Gouny S, Felician O, Soulier E, Cozzone P, Ceccaldi M, Poncet M. (2008) Grey matter loss in amnestic MCI patients according to their profile of memory impairment. Neuropsychologia, 46, 1009-1019. |
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Guedj E,
Barbeau E, Didic M, Felician O, de Laforte C, Ceccaldi M, Mundler O,
Poncet M. (2006). Identification of subgroups in amnestic Mild
Cognitive Impairment. Neurology, 67, 356358. |
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Barbeau E, Didic M, Tramoni E, Felician O, Joubert S, Sontheimer A, Ceccaldi M, Poncet M. (2004). Evaluation of visual recognition memory in MCI patients. Neurology, 62, 1317-1322. |
Some of our studies in which the DMS48 was used
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Barbeau EJ, Pariente J, Felician O, Puel M. (2011). Visual recognition memory: a double anatomo-functional dissociation. Hippocampus, 21(9), 929-934. |
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Barbeau EJ, Didic M, Felician O, Tramoni E, Guedj E, Ceccaldi M, Poncet M. (2006). Pure progressive amnesia: An atypical amnestic syndrome? Cognitive Neuropsychology, 23(8), 12301247. |
Book chapters on the DMS48 (available on request)
Barbeau EJ, Ceccaldi M. (2010). Lévaluation des troubles de la mémoire
au stade prédémentiel de la maladie dAlzheimer : le DMS48. Neurologie.com,
2(6), 1-3.
Barbeau EJ, Guedj E, Felician O, Didic M,
Ranjeva JP, Poncet M and Ceccaldi M. (2007). Assessing memory impairment in
early Alzheimers disease: the DMS48. In Vellas B, Grundman M, Feldman H,
Fitten LJ, Winblad B, Giacobini E (Eds). Research and Practice in Alzheimer's
Disease and Other Dementias. Vol. 12. Paris, Serdi
Publisher. p 134-138.
Barbeau
E, Felician O, Joubert S, Didic M, Poncet M, Ceccaldi M. (2006). Test de
reconnaissance d'images et maladie d'Alzheimer. In Michel BF, Verdureau F,
Dubois B (Eds). Images et démences. Monographie du Groupe de Recherche sur la
Maladie dAlzheimer. Marseille, éditions Solal. p 171-180.
Barbeau
E, Tramoni E, Joubert S, Mancini J, Ceccaldi M, Poncet M. (2004). Évaluation de
la mémoire de reconnaissance visuelle : normalisation dune nouvelle épreuve en
choix forcé et utilité en neuropsychologie clinique. In Ergis AM, Gely-Nargeot
MC, Van-der-Linden M (Eds) Les troubles de la mémoire dans la maladie
d'Alzheimer. Marseille, éditions Solal. p 85-101.
Acknowledgements
These studies are carried out in collaboration with the Service de Neurologie et de Neuropsychologie (Mira Didic, Olivier Felician, Mathieu Ceccaldi and Michel Poncet); Service Central de Biophysique et de Médecine Nucléaire (Eric Guedj) and CRMBM CNRS UMR 6612 (Jean-Philippe Ranjeva and Patrick Cozzone), AP-HM Timone, Marseille, France. They are supported by PHRC AP-HM 2001/54 and France Alzheimer.
Contact
emmanuel.barbeau "at" cnrs.fr
Personal page
Centre de Recherche Cerveau et Cognition (CERCO)
UMR 5549 (CNRS-UPS)
CHU Purpan Pavillon Baudot
31055 Toulouse Cedex 9
France